Trifluoromethyl alcohol and ketone inhibitors of metallo-β-lactamases

DOI: 10.1016/0960-894X(96)00453-2

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2455 - 2458 (1996)

Update date:2022-07-31

Topics:

Authors:

Walter, Magnus W.

Felici, Antonio

Galleni, Moreno

Soto, Raquel Paul

Adlington, Robert M.

Baldwin, Jack E.

Frere, Jean-Marie

Gololobov, Mikhail

Schofield, Christopher J.

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Article abstract of DOI:10.1016/0960-894X(96)00453-2

α-Amido trifluoromethyl alcohols and ketones were synthesised via two independent routes using Ruppert's Reagent (TMS-CF₃) and shown to be the first reported synthetic inhibitors of metallo-β-lactamases.

Full text of DOI:10.1016/0960-894X(96)00453-2

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