Preparation of eight-membered cyclic ethers by Lewis acid promoted acetal-alkene cyclizations

DOI: 10.1021/ja00167a041

Source and publish data:

Journal of the American Chemical Society p. 4386 - 4399 (1990)

Update date:2022-09-26

Topics: Lewis acid NMR spectroscopy Cyclization Preparation Reaction Optimization Catalyst Screening Gas Chromatography

Authors:

Blumenkopf, Todd A.

Bratz, Matthias

Casta?eda, Armando

Look, Gary C.

Overman, Larry E.

Rodriguez, Domingo

Thompson, Andrew S.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00167a041

The Lewis acid promoted cyclization of 20 5-alkenyl acetals is reported. Oxocenes with Δ⁴ unsaturation (3,6,7,8-tetrahydro-2H-oxocins) can be accessed in this convenient fashion with moderate to excellent efficiency and with perfect regiochemic

Full text of DOI:10.1021/ja00167a041

Products guided by the article

Product name:tert-Butyl-dimethyl-(1-methyl-5-phenylsulfanyl-hex-5-enyloxy)-silane

Cas No:127333-83-9

R&D Labs maybe for 127333-83-9

Yancheng Smiling Imp & Exp Co., Ltd.

Contact:+86-515-83173586

Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Jai Radhe Sales

website:http://www.jairadhesales.com

Contact:0091-79-26431096

Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
A.M FOOD CHEMICAL CO., LIMITED

Contact:86-531-87100375

Address:20Floor，Bblock，1Building，pharma-valley，Jinan，China
Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai
Rugao Jinling Chemical Co., Ltd.(expird)

Contact:0086-513-68005586

Address:Lianluo new village huangshi town Rugao city Jiangsu Province.

Relevant to this article

Homoisoflavonoids: Natural scaffolds with potent and selective monoamine oxidase-B inhibition properties

Doi:10.1021/jm1013709
(2011)
Synthesis of the C22-C37 segment of prorocentin

Doi:10.1016/j.tetlet.2011.01.042
(2011)
Synthesis of Highly Functionalized Flavones and Chromones Using Cycloacylation Reactions and C-3 Functionalization. A Total Synthesis of Hormothamnione

Doi:10.1021/jo00301a027
(1990)
Fused phenanthridines: Domino cyclization of 1,6-diynes with bromo(iso)quinoline

Doi:10.1002/asia.201000692
(2011)
An efficient α-hydroxylation of carbonyls using the HOF·CH₃CN complex

Doi:10.1016/S0040-4020(98)01173-9
(1999)
Heterosubstituted Anthracene-9,10-dione Analogues. The Synthesis and Antitumor Evaluation of 5,8-Bis<(aminoalkyl)amino>naphtho<2,3-b>thiophene-4,9-diones

Doi:10.1021/jm00171a048
(1990)

Article Doi