Stereoselective Synthesis of 2,3-Diamino Acids. 2,3-Diamino-4-phenylbutanoic Acid

DOI: 10.1021/jo00304a011

Source and publish data:

Journal of Organic Chemistry p. 5017 - 5025 (1990)

Update date:2022-09-26

Topics:

Authors:

Dunn, Peter J.

Haener, Robert

Rapoport, Henry

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Article abstract of DOI:10.1021/jo00304a011

The synthesis of (2S,3S)- and (2S,3R)-2,3-diamino-4-phenylbutanoic acid (1c and 3) from L-aspartic acid is described.The N-(phenylfluorenyl)-protected aspartic acid diesters 4 and 10 (α-tert-butyl, β-methyl), 18 (β-benzyl, α-tert-butyl), and 28 (β-benzyl,

Full text of DOI:10.1021/jo00304a011

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