α-Trifluormethyl Substituted Amino Acids with Alkyne Functions in the Side Chain

Article abstract of DOI:10.1055/s-1990-26803

Starting from trifluoro pyruvates and terminal alkynes a simple preparative procedure for synthesis of α-trifluoromethyl substituted acetylenic α-amino acids and α,ω-diamino dicarboxylic acids is described.The triple bond in the side chain can be function