Hydroxyperfluoroazobenzenes: Novel inhibitors of enzymes of androgen biosynthesis

DOI: 10.1021/jm00171a019

Source and publish data:

Journal of Medicinal Chemistry p. 2452 - 2455 (1990)

Update date:2022-08-03

Topics:

Authors:

Jarman Jarman

Barrie Barrie

Deadman Deadman

Houghton

McCague McCague

Rowlands

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Article abstract of DOI:10.1021/jm00171a019

In a search for inhibitors of 17α-hydroxylase-C_17,20-lyase and testosterone-5α-reductase, target enzymes in the development of drugs to treat hormone-dependent prostatic cancer, we have identified certain compounds chemically derived by the hyd

Full text of DOI:10.1021/jm00171a019

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