Hydroxyperfluoroazobenzenes: Novel inhibitors of enzymes of androgen biosynthesis

DOI: 10.1021/jm00171a019

Source and publish data:

Journal of Medicinal Chemistry p. 2452 - 2455 (1990)

Update date:2022-08-03

Topics:

Authors:

Jarman Jarman

Barrie Barrie

Deadman Deadman

Houghton

McCague McCague

Rowlands

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a019

In a search for inhibitors of 17α-hydroxylase-C_17,20-lyase and testosterone-5α-reductase, target enzymes in the development of drugs to treat hormone-dependent prostatic cancer, we have identified certain compounds chemically derived by the hyd

Full text of DOI:10.1021/jm00171a019

Products guided by the article

Product name:cis-4,4'-dihydroxyoctafluoroazobenzene

Cas No:129492-99-5

R&D Labs maybe for 129492-99-5

Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
Changsha Yihai Chemical Technology Co.,ltd

website:http://www.cs-yihai.com/

Contact:0731- 85620465

Address:Room 23005, unit 2, the northern building of Xiangsong international building , NO.259 Shaoshan Road , Changsha , Hunan, China.(mainland)
Guangzhou Puho Pharmaceutical Technology Co. Ltd.

Contact:86-20-29848035/29848075

Address:No.166, Chaoyang East Road, Panyu District, Guangzhou City, Guangdong Province
Airsea(Taizhou) Pharmaceutical Limited(expird)

Contact:+86-576-88057622

Address:Dubei, Duqiao, Linhai, Taizhou, Zhejiang, China Zip: 317016
Geen Chemical Technology Co., Ltd

Contact:86-769-21660847

Address:1408, Yingfeng Commercial Center, Nancheng District

Relevant to this article

The synthesis of the 8-C-substituted 2,6-diamino-9-[2-(phosphonomethoxy) ethyl]purine (PMEDAP) derivatives by diverse cross-coupling reactions

Doi:10.1139/V11-001
(2011)
Facile synthesis of σ-π Conjugated organosilicon polymers via Click polymerization

Doi:10.1016/j.jorganchem.2011.02.028
(2011)
Synthesis and carbonic anhydrase isoenzymes i and II inhibitory effects of novel benzylamine derivatives

Doi:10.3109/14756366.2012.763163
(2014)
Palladium-catalyzed synthesis of N-arylated carbazoles using anilines and cyclic diaryliodonium salts

Doi:10.3762/bjoc.9.136
(2013)
Doi:10.1039/jr9610001429
(1961)
Preparation of Optically Active 6'-Fluorocarbocyclic Nucleosides utilising an Enantiospecific Enzyme-catalysed Baeyer-Villiger Type Oxidation

Doi:10.1039/c39900000619
(1990)

Article Doi