Asymmetric Total Synthesis of (-)-Secodaphniphylline

DOI: 10.1021/jo00307a006

Source and publish data:

Journal of Organic Chemistry p. 5433 - 5434 (1990)

Update date:2022-08-05

Topics:

Authors:

Stafford, Jeffrey A.

Heathcock, Clayton H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00307a006

An asymmetric total synthesis of (-)-secodaphniphyllin (5) is described.The desired absolute stereochemistry is established in two stereoselective transformations - an asymmetric Michael reaction of amide 8 and an asymmetric reduction of ketone 14.

Full text of DOI:10.1021/jo00307a006

Products guided by the article

Product name:Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate

Cas No:129539-97-5

R&D Labs maybe for 129539-97-5

Nanjing yieldpharma co.ltd

Contact:13813902930 025-52714267

Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Nanjing Chemlin Chemical Co., Ltd.

website:http://www.echemlin.cn

Contact:+86-25-83697070

Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Nanjing Hemings New Material Tech Co.,Ltd.

Contact:+86-25-86606739

Address:NO.186 Jiangdong Mid Road,Nanjing China
Zhejiang Kaili Industrial Co., Ltd

Contact:+86-571-85241926

Address:lantian business center,No.18 Moganshan Road
Anhui Gusheng Import&Export CO.,LTD

Contact:86-551-63662296

Address:Jinzhai Road NO.162 ,hefei, china

Relevant to this article

Development of 2,4-diaminopyrimidine derivatives as novel SNSR4 antagonists

Doi:10.1016/j.bmcl.2011.01.138
(2011)
Synthesis of Isoquinoline Derivatives by a Tandem Aza-Wittig/Electrocyclization Strategy and Preparation of the Unknown 1,9-Diazaphenalene Ring by a Consecutive Electrocyclic Ring Closure/Claisen Rearrangement/Intramolecular Amination Process

Doi:10.1021/jo00312a020
(1990)
Coordination polymers of various architectures built with mixed imidazole/benzimidazole and carboxylate donor ligands and different metal ions: Syntheses, structural features and magnetic properties

Doi:10.1039/c0nj00302f
(2010)
Synthesis of multifunctionalized building blocks via vinylogous addition of Chan's diene to carbonyl and carbonyl-related electrophiles, mediated by molecular iodine

Doi:10.1016/j.tet.2011.02.036
(2011)
SYNTHESIS OF FURAN COMPOUNDS WITH AMINO AND IMINO GROUPS AT THE β-POSITION OF THE SIDE CHAIN BY THE CATALYTIC HYDROFORMAMINATION OF 2-VINYLFURAN

Doi:10.1007/BF00962410
(1990)
Sulfinic Acids and Related Compounds 23. Preparation of Sulfinic Acids by the Reaction of Sulfonyl Halides with Thiols

Doi:10.1055/s-1990-26884
(1990)

Article Doi