Synthesis and Characterization of a Novel Lysosomotropic Enzyme Substrate That Fluoresces at Intracellular pH

Article abstract of DOI:10.1021/jo00001a008

Fluorogenic substrates that can be used to detect the activity of enzymes within intact cells are needed for biochemical investigations of human lysosomal storage disorders and identification of gene transfer recombinants.The first member of a new series