Synthesis and Biological Evaluation of Dipeptidyl and Tripeptidyl Polyoxin and Nikkomycin Analogues as Anticandidal Prodrugs

DOI: 10.1021/jm00105a026

Source and publish data:

Journal of Medicinal Chemistry p. 174 - 180 (1991)

Update date:2022-08-02

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Authors:

Krainer, Eduardo

Becker, Jeffrey M.

Naider, Fred

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Article abstract of DOI:10.1021/jm00105a026

Nine analogues (1-5, 9-12) of the peptidyl nucleoside antibiotics nikkomycin and polyoxin were synthesized and tested for their biological properties against different strains of the pathogenic yeast Candida albicans.The tripeptidyl series of analogues (1

Full text of DOI:10.1021/jm00105a026

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