Synthesis and Biological Evaluation of Dipeptidyl and Tripeptidyl Polyoxin and Nikkomycin Analogues as Anticandidal Prodrugs

DOI: 10.1021/jm00105a026

Source and publish data:

Journal of Medicinal Chemistry p. 174 - 180 (1991)

Update date:2022-08-02

Topics:

Authors:

Krainer, Eduardo

Becker, Jeffrey M.

Naider, Fred

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00105a026

Nine analogues (1-5, 9-12) of the peptidyl nucleoside antibiotics nikkomycin and polyoxin were synthesized and tested for their biological properties against different strains of the pathogenic yeast Candida albicans.The tripeptidyl series of analogues (1

Full text of DOI:10.1021/jm00105a026

Products guided by the article

Product name:(S)-((S)-2-Benzyloxycarbonylamino-6-octanoylamino-hexanoylamino)-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-acetic acid

Cas No:130932-95-5

R&D Labs maybe for 130932-95-5

sichuan tiancai fine co LTD.

website:http://www.tcfinechem.com/

Contact:18681346930

Address:baifu town,whou district
Hangzhou Kai Peng Biotechnology Co., Ltd.

Contact:86-571-89939007

Address:NO. 499, Wensan West Road, Xihu District, Hangzhou, 310012, China
HENAN NEW BLUE CHEMICAL CO.,LTD

website:http://www.newbluechem.com

Contact:86-371-55170693/55170694

Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China
Guangzhou Reachin Chemical Co., Ltd

Contact:+86-20-37087379 ext.604

Address:A122C-1, Tianyuan Plaza, 401 Tianyuan Rd., Tianhe, Guangzhou, China
Changzhou Litong Chemical Co., Ltd.

website:http://www.litonchem.com/

Contact:+86-519-86301238

Address:Laoba Rd, Hutang town Changzhou Jiangsu

Relevant to this article

Utilization of IndPHOX-ligands in palladium-catalysed asymmetric allylic aminations

Doi:10.1016/j.tetasy.2011.03.004
(2011)
Cyclopropenylidene carbene ligands in palladium catalysed coupling reactions: Carbene ligand rotation and application to the Stille reaction

Doi:10.1039/c1dt10109a
(2011)
Intramolecular cyclization of a phosphinoazide: Transformation of 1,2,3,4-triazaphosphole into 1,2,4-diazaphosphole

Doi:10.1080/10426507.2010.507732
(2011)
An efficient route to 2,3-disubstituted indoles via reductive alkylation using H₂ as reductant

Doi:10.1016/j.tetlet.2011.03.099
(2011)
Synthesis and antitumor activity of new retinobenzoic acids

Doi:10.1002/cbdv.201000116
(2011)
Synthetic utility of bifunctional thiophene derivatives and antimicrobial evaluation of the newly synthesized agents

Doi:10.1007/s00706-011-0456-z
(2011)

Article Doi