N-(4-isoxazolylthiazol-2-yl)oxamic acid derivatives as potent orally active antianaphylactic agents

DOI: 10.1021/jm00106a020

Source and publish data:

Journal of Medicinal Chemistry p. 600 - 605 (1991)

Update date:2022-08-05

Topics: Derivatives Potent Orally Active Experimental Oxamic acid

Authors:

Chiarino

Grancini

Frigeni Frigeni

Biasini Biasini

Carenzi Carenzi

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Article abstract of DOI:10.1021/jm00106a020

A series of N-(4-isoxazolylthiazol-2-yl)oxamic acid derivatives was synthesized and tested on the passive cutaneous anaphylaxis (PCA) model in rats to verify its potential antianaphylactic activity. These compounds were prepared by reaction of an appropri

Full text of DOI:10.1021/jm00106a020

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Product name:5-(2,2-Dibromo-acetyl)-isoxazole-3-carboxylic acid ethyl ester

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