DIRECT DETECTION OF TWO METAPHOSPHORAMIDATES IN -75 DEG C THF SOLUTIONS BY 31P NMR SPECTROSCOPY

Article abstract of DOI:10.1016/S0040-4039(00)97094-1

2,3-Oxaphosphabicyclo<2.2.2>oct-5-ene-3-oxide derivatives with Et2N- or Mesityl NH groups on phosphorus undergo fragmentation readily when irradiated at -75 deg C in tetrahydrofuran.The solutions give 31P NMR signals at δ +12 and +9, respectively, which are attributed to solvated metaphosphoramidates (RR'N-PO2).These are rapidly converted to phosphoramidates (EtO-P(O)(OH)(NRR') on addition of ethanol.