Journal of Medicinal Chemistry p. 1538 - 1544 (1991)
Update date:2022-09-26
Topics:
Dow
Bechle
Chou
Clark
Hulin
Stevenson
A series of benzyloxazolidine-2,4-diones, containing oxazole-based side chains, were found to lower blood glucose levels in the genetically obese ob/ob mouse. Incorporation of a benzofuran structural element in these compounds provides greatly enhanced in vivo potency. The syntheses and structure-activity relationships for this series are detailed.
View MoreZHEJIANG CHEMICAL INDUSTRY INSTITUTE TECHNOLOGY CO.,LTD(expird)
Contact:86-575-82730298
Address:shangyu
Qingzhou Baibang import and export co.,Ltd
Contact:+86-536-3265899
Address:No.338, Tuoshan Road
Wuhan Konberd Biotech Co., Ltd.
Contact:+86-27-87205925
Address:NO.666, Gaoxin Road, Eastlake High-tech zone
NANCHANG QINZHI SCI&TEC.CO.,LTD(expird)
Contact:+86-13687004106
Address:Hero South Road,Hero Zone,Nanchang,Jiangxi,China
website:http://www.tcfinechem.com/
Contact:18681346930
Address:baifu town,whou district
Doi:10.1021/ja01591a049
(1956)Doi:10.1016/j.carres.2013.04.008
(2013)Doi:10.1016/0022-328X(91)80081-T
(1991)Doi:10.1021/jm200608k
(2011)Doi:10.1016/j.bmcl.2014.10.031
(2014)Doi:10.1016/j.saa.2011.04.089
(2011)
