N,N-Diethylfluoromethyltamoxifen: Synthesis, assignment of 1H and 13C spectra and receptor assay

DOI: 10.1016/0223-5234(92)90023-T

Source and publish data:

European Journal of Medicinal Chemistry p. 919 - 924 (1992)

Update date:2022-08-03

Topics:

Authors:

Yang Yang

Cherif Cherif

Tansey Tansey

Kuang Kuang

Wright Wright

Kim Kim

Wallace Wallace

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Article abstract of DOI:10.1016/0223-5234(92)90023-T

(cis) and (trans)N,N-diethylfluoromethyltamoxifen (1-[4-(2-diethylaminoethoxy)phenyl]-1,2-diphenyl-5-fluoro-1-pentene) were synthesized from clomiphene in a three-step procedure and both isomers were differentiated by the concerted application of two-dime

Full text of DOI:10.1016/0223-5234(92)90023-T

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