
Tetrahedron Letters p. 843 - 846 (1991)
Update date:2022-08-02
Topics:
Ward, Dale E.
Kaller, Brian F.
3-phenylthio-2-(trimethylsilymethyl)propene is a convenient conjunctive reagent for the preparation of methylenecyclohexanes via a [3+3] annulation. The trimethylsilyl group facilitates the Lewis acid catalyzed allylation of an aldehyde or acetal while the phenylthio group directs a 6-endo-trig radical cyclization reaction.
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(1991)