Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine by data-dependent tandem mass spectrometry

DOI: 10.1021/tx300253j

Source and publish data:

Chemical Research in Toxicology p. 2179 - 2193 (2012)

Update date:2022-07-30

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Authors:

Peng, Lijuan

Dasari, Surendra

Tabb, David L.

Turesky, Robert J.

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Article abstract of DOI:10.1021/tx300253j

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic aromatic amine that is formed during the cooking of meats. PhIP is a potential human carcinogen: it undergoes metabolic activation to form electrophilic metabolites that bind to DNA

Full text of DOI:10.1021/tx300253j

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