Synthesis and anticonvulsant activities of α-acetamido-N-benzylacetamide derivatives containing an electron-deficient α-heteroaromatic substituent

DOI: 10.1021/jm00052a017

Source and publish data:

Journal of Medicinal Chemistry p. 4567 - 4571 (1994)

Update date:2022-09-26

Topics:

Authors:

Bardel Bardel

Bolanos Bolanos

Kohn Kohn

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00052a017

Recent studies have demonstrated that C(α)-substituted α-acetamido-N- benzylacetamides displayed excellent anticonvulsant activities in mice. Analysis of the structure-activity relationship for this series of compounds has shown that placement of small, e

Full text of DOI:10.1021/jm00052a017

Products guided by the article

Product name:α-acetamido-N-benzyl-α-bromoacetamide

Cas No:133873-18-4

R&D Labs maybe for 133873-18-4

shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Chengdu Sino-Strong Pharmaceutical Co.,Ltd.

website:http://www.sino-strong.com.cn

Contact:+86-28-82666753

Address:459 West haike road,Cross-straits technological industry park, Wenjiang district,Chengdu, P.R.China
Shanghai WinTide BioTechnology Co.,Ltd

Contact:86-21-37100630

Address:No. 908 Yunhe Road, Fengxian district, Shanghai
Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.
Xinjiang Zhongtai Chemical Co., Ltd.

Contact:+86-991-8788172

Address:NO.78 XISHAN RD.URUMQI，CHINA

Relevant to this article

Novel approach towards 2-substituted aminobenzimidazoles on imidazolium ion tag under focused microwave irradiation

Doi:10.1016/j.tet.2011.06.068
(2011)
Copper-catalyzed coupling of imidazoles and pyrazoles with 1,1-dibromo-1-alkenes: A distinct approach for direct N-alkynylation of heteroarenes

Doi:10.1016/j.tetlet.2011.09.117
(2011)
Anti-Markovnikov Oxidation of β-Alkyl Styrenes with H₂O as the Terminal Oxidant

Doi:10.1021/jacs.6b07411
(2016)
Structurally diverse α-substituted benzopyran synthesis through a practical metal-free C(sp³)-H functionalization

Doi:10.1021/ol503004a
(2014)
Synthesis and antifungal activity of some new benzimidazole derivatives

Doi:10.1002/ardp.19913240505
(1991)
Design and synthesis of trans-3-aminopyran-2-carboxylic acid (APyC) and α/β-peptides with 9/11-helix

Doi:10.1039/c1ob06279d
(2011)

Article Doi