Synthesis and anticonvulsant activities of α-acetamido-N-benzylacetamide derivatives containing an electron-deficient α-heteroaromatic substituent

Article abstract of DOI:10.1021/jm00052a017

Recent studies have demonstrated that C(α)-substituted α-acetamido-N- benzylacetamides displayed excellent anticonvulsant activities in mice. Analysis of the structure-activity relationship for this series of compounds has shown that placement of small, e