Preparation and anticonvulsant activity of a series of functionalized α-heteroatom-substituted amino acids

DOI: 10.1021/jm00112a020

Source and publish data:

Journal of Medicinal Chemistry p. 2444 - 2452 (1991)

Update date:2022-08-04

Topics:

Authors:

Kohn Kohn

Sawhney Sawhney

LeGall LeGall

Robertson

Leander Leander

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Article abstract of DOI:10.1021/jm00112a020

Potent anticonvulsant activity has been reported for (R,S)-2-acetamido-N-benzyl-2-methylacetamide (2a). Select α-heteroatom substituted derivatives of 2a have been prepared (26 examples) in which the α-methyl group has been replaced by nitrogen (3a-q), ox

Full text of DOI:10.1021/jm00112a020

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