Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n- propylamino)tetralin

DOI: 10.1021/jm00058a003

Source and publish data:

Journal of Medicinal Chemistry p. 671 - 682 (1993)

Update date:2022-08-03

Topics:

Authors:

Lin Lin

Haadsma-Svensson

Lahti Lahti

McCall McCall

Piercey Piercey

Schreur Schreur

Von Voigtlander

Chidester

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00058a003

The synthesis and structure-activity relationships (SAR) of C-1- or C-3- substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH- DPAT) are described. These analogs were synthesized via alkylation of the tetralone derivatives followed by r

Full text of DOI:10.1021/jm00058a003

Products guided by the article

Product name:Toluene-4-sulfonic acid 2-(allyl-propyl-amino)-8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl ester

Cas No:134468-20-5

R&D Labs maybe for 134468-20-5

Shanghai Dynamic Industrial Co.,Ltd.

website:http://www.shdynamic.com

Contact:86-021 3392 6680

Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071
Shanghai chemrole co.,ltd

Contact:021-50278900

Address:No.6,Room 201 ,Lane 299,bisheng road ,shanghai ,china
zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China

Relevant to this article

Allyl complexes of scandium: Synthesis and structure of neutral, cationic and anionic derivatives

Doi:10.1039/c1cc14180e
(2011)
4-methoxybenzyloxymethyl group, a racemization-resistant protecting group for cysteine in fmoc solid phase peptide synthesis

Doi:10.1021/ol300592w
(2012)
Synthesis and characterization of poly(5,8-quinoxaline ethynylene)s

Doi:10.1021/ma201347z
(2011)
Design, synthesis and insight into the structure-activity relationship of 1,3-disubstituted indazoles as novel HIF-1 inhibitors

Doi:10.1016/j.bmcl.2011.08.120
(2011)
Bronsted acid-promoted sequential hydroarylation-hydroamidation of arene-tethered 1-(2-alkynylphenyl)ureas: Direct access to 4,4-spiro-3,4-dihydro- 2-(1H)-quinazolinones

Doi:10.1002/adsc.201100223
(2011)
Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y₆ receptor antagonists

Doi:10.1016/j.bmcl.2021.128008
(2021)

Article Doi