Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n- propylamino)tetralin

DOI: 10.1021/jm00058a003

Source and publish data:

Journal of Medicinal Chemistry p. 671 - 682 (1993)

Update date:2022-08-03

Topics:

Authors:

Lin Lin

Haadsma-Svensson

Lahti Lahti

McCall McCall

Piercey Piercey

Schreur Schreur

Von Voigtlander

Chidester

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00058a003

The synthesis and structure-activity relationships (SAR) of C-1- or C-3- substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH- DPAT) are described. These analogs were synthesized via alkylation of the tetralone derivatives followed by r

Full text of DOI:10.1021/jm00058a003

Products guided by the article

Product name:Toluene-4-sulfonic acid 2-(allyl-propyl-amino)-8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl ester

Cas No:134468-20-5

R&D Labs maybe for 134468-20-5

Shandong Hongxiang Zinc Co., Ltd

Contact:086-0311-66187879

Address:DaWang developing zone
Wuxi Olite Chemical Co., Ltd.

Contact:86-510-82853889

Address:Rm.3732, No.18-2,Yonghe Rd.,Wuxi,Jiangsu,214023,China
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.
Shanghai Profirst Co., Ltd.

Contact:+86-21-38122007

Address:2, Lane 1123, Kangqiao Road, Pudong New Area, Shanghai

Relevant to this article

Allyl complexes of scandium: Synthesis and structure of neutral, cationic and anionic derivatives

Doi:10.1039/c1cc14180e
(2011)
4-methoxybenzyloxymethyl group, a racemization-resistant protecting group for cysteine in fmoc solid phase peptide synthesis

Doi:10.1021/ol300592w
(2012)
Synthesis and characterization of poly(5,8-quinoxaline ethynylene)s

Doi:10.1021/ma201347z
(2011)
Design, synthesis and insight into the structure-activity relationship of 1,3-disubstituted indazoles as novel HIF-1 inhibitors

Doi:10.1016/j.bmcl.2011.08.120
(2011)
Bronsted acid-promoted sequential hydroarylation-hydroamidation of arene-tethered 1-(2-alkynylphenyl)ureas: Direct access to 4,4-spiro-3,4-dihydro- 2-(1H)-quinazolinones

Doi:10.1002/adsc.201100223
(2011)
Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y₆ receptor antagonists

Doi:10.1016/j.bmcl.2021.128008
(2021)

Article Doi