Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n- propylamino)tetralin

DOI: 10.1021/jm00058a003

Source and publish data:

Journal of Medicinal Chemistry p. 671 - 682 (1993)

Update date:2022-08-03

Topics:

Authors:

Lin Lin

Haadsma-Svensson

Lahti Lahti

McCall McCall

Piercey Piercey

Schreur Schreur

Von Voigtlander

Chidester

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Article abstract of DOI:10.1021/jm00058a003

The synthesis and structure-activity relationships (SAR) of C-1- or C-3- substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH- DPAT) are described. These analogs were synthesized via alkylation of the tetralone derivatives followed by r

Full text of DOI:10.1021/jm00058a003

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