Synthesis of novel N-aroyl- and N-arylsulfonylisothiazole-2-imines by cyclization of thiocyanatovinylaldehyde hydrazones

Article abstract of DOI:10.1016/S0040-4039(00)91960-9

The synthesis of N-aroyl- and N-arylsulfonylthiazole-2-imines 7c-f as well as the corresponding acceptor-substituted 2-aminoisothiazolium salts 8c-f by cyclocondensation of thiocyanatovinylaldehyde hydrazones 6c-f is reported. The alternative cyclization