Amnesia-reversal activity of a series of 5-alkoxy-1-arylsulfonyl-2-pyrrolidinones

DOI: 10.1016/0223-5234(91)90101-R

Source and publish data:

European Journal of Medicinal Chemistry p. 403 - 413 (1991)

Update date:2022-09-26

Topics:

Authors:

Toja, E Toja, E

Gorini, C

Zirotti, C

Barzaghi, F

Galliani, G

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Article abstract of DOI:10.1016/0223-5234(91)90101-R

A series of 5-alkoxy-1-arylsulfonyl-2-pyrrolidinones were prepared by condensation of arylsulfonyl chlorides with 5-alkoxy-2-pyrrolidinones.Most compounds reversed electroconvulsive shock-induced amnesia in mice, showing the typical inverted U-shaped dose

Full text of DOI:10.1016/0223-5234(91)90101-R

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