Tetrahedron p. 19 - 32 (1992)
Update date:2022-08-03
Topics:
Taylor, Edward C.
Schrader, Thomas H.
Walensky, Loren D.
Several novel and very potent folate antimetabolites, structurally based upon our previously described "open-chain" version of DDATHF but carrying 1-carbon substituents in the 10-position, have been synthesized. A key synthetic sequence involving a pallad
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