Asymmetric Amination of Carboxylic Acids via a Diels-Alder Strategy.

DOI: 10.1016/S0040-4039(00)92382-7

Source and publish data:

Tetrahedron Letters p. 5349 - 5352 (1991)

Update date:2022-08-04

Topics:

Authors:

Gouverneur, Veronique

Ghosez, Leon

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Article abstract of DOI:10.1016/S0040-4039(00)92382-7

2-Azadienes 1 which are readily prepared from acyl chlorides react with high facial selectivity with the chiral carbamoyl nitroso dienophile 2.Reduction and hydrolysis of the adducts yield enantiomerically pure amino acids.

Full text of DOI:10.1016/S0040-4039(00)92382-7

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