3,4-Dihydro-3-amino-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. 1. Synthesis and Structure-Activity Relationship Studies

DOI: 10.1021/jm00038a007

Source and publish data:

Journal of Medicinal Chemistry p. 1779 - 1793 (1994)

Update date:2022-09-26

Topics: Synthesis Structure-activity relationship studies

Authors:

Podona, Tchao

Guardiola-Lemaitre, Beatrice

Caignard, Daniel-Henri

Adam, Gerard

Pfeiffer, Bruno

et al. et al.

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Article abstract of DOI:10.1021/jm00038a007

A series of 3,4-dihydro-3-amino-2H-1-benzopyran derivatives were prepared in order to determine the necessary structural requirements for good affinity for 5-HT_1A receptors and high selectivity versus other receptors.Modifications of the extrac

Full text of DOI:10.1021/jm00038a007

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