A-ring aromatic 9,10-secosteroids by radical-induced fragmentation of 3-oxo-1,4-diene derivatives

Article abstract of DOI:10.1016/0040-4039(91)80488-R

For nine steroid representatives in the 3-oxo-1,4-diene series, the majority of which bears a methyl substituent at C(1), it is shown that both tri-n-butyltin hydride and tris(trimethylsilyl)silane promote C(9)-C(10) bond cleavage in the presence of a rad