Stereoselective Synthesis of Trifluoromethylated Compounds with Controlled Adjacent Tertiary Carbons by Michael Addition to (E)-3-(Trifluoromethyl)acrylates

DOI: 10.1021/jo00119a013

Source and publish data:

Journal of Organic Chemistry p. 4363 - 4374 (1995)

Update date:2022-08-03

Topics:

Authors:

Shinohara, Noriyasu

Haga, Jiro

Yamazaki, Takashi

Kitazume, Tomoya

Nakamura, Shinichiro

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Article abstract of DOI:10.1021/jo00119a013

Michael addition reaction of various lithium enolates to ethyl (E)-3-(trifluoromethyl)acrylate (E)-1 was found to be one of the most effective routes to construct materials not only with a CF3 group but also readily distinguishable multiple functionalitie

Full text of DOI:10.1021/jo00119a013

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