One-pot synthesis of rufloxacin

Article abstract of DOI:10.1080/00397919108021589

Rufloxacin (MF-934) was prepared in one-pot synthesis in 61% yield by treatment of the 2,3,5-trifluoro-4-(4-methyl-1-piperazinyl)-benzoyl acetate, first with N,N-dimethylformamide dimethyl acetal, then with 2-aminoethanethiol, followed by cyclization and

Full text of DOI:10.1080/00397919108021589

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Synthetic Communications:
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One-Pot Synthesis of
Rufloxacin
V. Cecchetti a , A. Fravolini a & F. Schiaffella a
a Istituto di Chimica, Farmaceutica e Tecnica
Farmaceutica Università di Perugia , 06100,
Perugia, Italy
Published online: 23 Sep 2006.
To cite this article: V. Cecchetti , A. Fravolini & F. Schiaffella (1991) One-Pot
Synthesis of Rufloxacin, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 21:22, 2301-2308, DOI:
10.1080/00397919108021589
To link to this article: http://dx.doi.org/10.1080/00397919108021589
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