A Novel Method for Preparation of Optically Active Dipeptide. Chemo- and Stereoselective Reduction of 2-Hydroxyimino Amides with Samarium Diiodide

Article abstract of DOI:10.1246/cl.1992.181

Various α,β-unsaturated amides derived from α-amino acids are converted to the corresponding 2-hydroxyimino amides of α-amino acids by the reaction with butyl nitrite and silane, which are directly reduced with samarium diiodide to the optically active di