Synthetic Communications p. 1017 - 1021 (1992)
Update date:2022-07-29
Topics:
Williams
α-Methylene-β-lactams are prepared by a Peterson olefination reaction. These substrates can be epoxidized with MCPBA to give the title dispiro-epoxy-β-lactams. Under the influence of boron trifluoride, these substrates rearrange to spiro-3-ketolactams.
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