
Journal of Heterocyclic Chemistry p. 565 - 568 (1994)
Update date:2022-08-04
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A convenient general method for the synthesis of a new heterocycle, spiro[azetidine-2,4'(1'H)-isoquinoline-1',3',4(2'H)-trione] is described. The key intermediate 2 was prepared by direct halogenation of position-4 of acid 3 with thionyl chloride, and sub
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