Enantioselective syntheses of (+)-methyl nonactate and (-)-methyl 8-epi-nonactate via asymmetric cycloadditive route

Article abstract of DOI:10.1016/S0040-4039(00)92241-X

Enantioselective routes to (+)-methyl nonactate (2 and (-)-methyl 8-epi-nonactate (3) are described. The cornerstone of this synthetic strategy is a combination of asymmetric silyl nitronate cycloaddition and asymmetric reduction, which provides the key s