Synthetic studies on spider neurotoxins (I): Total synthesis of nephilatoxins (NPTX-9) and NPTX-11, new neurotoxins of Joro spider (Nephila clavata)

DOI: 10.1016/S0040-4039(00)78872-1

Source and publish data:

Tetrahedron Letters p. 2833 - 2836 (1992)

Update date:2022-08-04

Topics:

Authors:

Miyashita, Masaaki

Sato, Hideaki

Yoshikoshi, Akira

Toki, Takashi

Matshushita, Masayuki

Irie, Hiroshi

Yanami, Tetsuji

Kikuchi, Yasuo

Takasaki, Chikahisa

Nakajima, Terumi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)78872-1

The first and efficient synthesis of Nephilatoxins (NPTX-9 and NPTX-11), new neurotoxins of Joro spider (Nephila clavata), has been achieved by employing a key azide intermediate as the polyamine unit.

Full text of DOI:10.1016/S0040-4039(00)78872-1

Products guided by the article

Product name:((S)-4-tert-Butoxycarbonylamino-4-{5-[(S)-3-carbamoyl-2-(2-1H-indol-3-yl-acetylamino)-propionylamino]-pentylcarbamoyl}-butyl)-carbamic acid benzyl ester

Cas No:142342-57-2

R&D Labs maybe for 142342-57-2

Taizhou Chemedir Biopharm-tech Co., Ltd

Contact:+86 523 86200218

Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China
Suzhou BEC Fine Chemicals Co., Ltd.

website:http://www.bek.com.cn

Contact:0512-68095917　 18913193865

Address:6, Jin Shan Road, Suzhou New District, 215011 China Suzhou Nations Pharmaceutical Innovation Center Inside
Hebei Tianxiang Biological & Pharmaceutical Co., Ltd

Contact:86-0312-6615158

Address:No 42 fazhan street qingyuan county
Shanghai united Scientific Co.,Ltd.

Contact:+86-21-53535353

Address:28F No.900 huaihai Road Shanghai China
TLS PHARMACEUTICAL CO.,LTD

Contact:0833-5590788/5590338/5590055

Address:Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark

Relevant to this article

Design and synthesis of diaziridinyl quinone thiadiazole hybrids via nitrile sulfide cycloaddition reaction as a key step

Doi:10.1016/j.tetlet.2016.02.082
(2016)
Regioselective synthesis of piperidinones by metal catalyzed ring expansion-carbonylation reactions. Remarkable cobalt and/or ruthenium carbonyl catalyzed rearrangement and cyclization reactions

Doi:10.1021/ja00044a010
(1992)
Gold phosphole complexes as efficient catalysts for alkyne activation

Doi:10.1021/om301244m
(2013)
HEXAFLUOROACETONE IN REACTION WITH 2-R-4-OXO-5,6-BENZO-1,3,2-DIOXAPHOSPHORINANES. A SIMPLE SYNTHETIC APPROACH TO FLUORINATED 1,3,2-DIOXAPHOSPHEPANES

Doi:10.1016/S0022-1139(00)83808-7
(1991)
New scalable and eco-friendly synthesis of gingerols

Doi:10.1016/j.tetlet.2012.03.092
(2012)
Remote stereocontrol by the sulfinyl group. Diels-Alder reaction of cyclopentadiene with substituted (S)-[2-(p-tolylsulfinyl)styrenes and (S)-[2-(p-tolylsulfinyl)phenyl] vinyl ketones

Doi:10.1016/j.tet.2012.03.112
(2012)

Article Doi