Fluoronaphthyridines as Antibacterial Agents. 6. Synthesis and Structure-Activity Relationships of New Chiral 7-(1-, 3-, 4-, and 6-Methyl-2,5-diazabicycloheptan-2-yl)naphthyridine Analogues of 7-heptan-2-yl>-1-(1,1-d

Article abstract of DOI:10.1021/jm00093a024

A series of novel chiral 7-(1-, 3-, 4-, and 6-methyl<(1R,4R)-2,5-diazabicyclo<2.2.1.>heptan-2-yl>-substituted naphthyridines has been prepared with the aim of obtaining good in vitro and in vivo antibacterial agents with a decrease of the pseudoallergic t