Tetrahedron p. 4769 - 4778 (1997)
Update date:2022-08-04
Topics: Diols Column chromatography NMR spectroscopy Chiral center Stereochemistry Recrystallization Catalytic hydrogenation Mass spectrometry (MS) Enantioselective synthesis Optical rotation HPLC (high-performance liquid chromatography) Protecting group Epoxidation Retrosynthetic analysis Epoxides C2-symmetric HIV protease inhibitors Synthetic yield
Gurjar, Mukund K.
Pal, Shashwati
Rama Rao
Pariza, Richard J.
Chorghade, Mukund S.
The Julia's olefination reaction between the sulfone derivative (10) and the aldehyde (13) (both obtained from L-phenylalanine) followed by debenzylation led to the formation (2S,5S,3E)-2,5-bis-[(1,1-dimethyl ethoxy)-carbonyl]amino-1,6-diphenylhex-3-ene (
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(2013)
