Substrate-related phosphonopeptides, a new class of thrombin inhibitors

DOI: 10.1016/0040-4039(91)80512-5

Source and publish data:

Tetrahedron Letters p. 7333 - 7336 (1991)

Update date:2022-08-04

Topics:

Authors:

Cheng Cheng

Goodwin Goodwin

Scully Scully

Kakkar Kakkar

Claeson Claeson

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Article abstract of DOI:10.1016/0040-4039(91)80512-5

Novel phosphorus-containing peptidomimetics, D-Aa-Pro-Aa(P)(OPh)₂, with lipophilic amino acids at the P₃ positions and amino phosphonic acids with neutral side chains in the P₁ position have been designed and synthesized as thrombin inhibitors.

Full text of DOI:10.1016/0040-4039(91)80512-5

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Product name:Z-D-Dpa-Pro-NHPGly^P(OPh)2

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