Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4

DOI: 10.1021/acs.jmedchem.8b00050

Source and publish data:

Journal of Medicinal Chemistry p. 6574 - 6591 (2018)

Update date:2022-08-15

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Authors:

Lamaa, Diana

Lin, Hsin-Ping

Zig, Lena

Bauvais, Cyril

Bollot, Guillaume

Bignon, Jér?me

Levaique, Helene

Pamlard, Olivier

Dubois, Joelle

Ouaissi, Mehdi

Souce, Martin

Kasselouri, Athena

Saller, Fran?ois

Borgel, Delphine

Jayat-Vignoles, Chantal

Al-Mouhammad, Hazar

Feuillard, Jean

Benihoud, Karim

Alami, Mouad

Hamze, Abdallah

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Article abstract of DOI:10.1021/acs.jmedchem.8b00050

Designing multitarget drugs have raised considerable interest due to their advantages in the treatment of complex diseases such as cancer. Their design constitutes a challenge in antitumor drug discovery. The present study reports a dual inhibition of tub

Full text of DOI:10.1021/acs.jmedchem.8b00050

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