3-Phenylpyrrolidines: synthesis and evaluation of the in vitro binding affinity at D1 and D2 receptors

DOI: 10.1016/0223-5234(92)90155-T

Source and publish data:

European Journal of Medicinal Chemistry p. 407 - 411 (1992)

Update date:2022-08-04

Topics:

Authors:

Crider, A M

Andersen, P H

Cruse, S F

Ghosh, D

Harpalani, A

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Article abstract of DOI:10.1016/0223-5234(92)90155-T

A variety of 3-phenylpyrrolidines were synthesized and evaluated for their dopamine binding affinity in rat striatal tissue in vitro using <3H> SCH 23390 and <3H> spiperone as the D1 and D2 selective radioligands, respectively.Maximal D1 and D2 receptor b

Full text of DOI:10.1016/0223-5234(92)90155-T

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