A Convenient Synthesis of Platelet-Activating Factors and Their Analogues from Chiral Epichlorohydrin

DOI: 10.1246/cl.1992.1417

Source and publish data:

Chemistry Letters p. 1417 - 1420 (1992)

Update date:2022-08-04

Topics:

Authors:

Tsuboi, Sadao

Takeda, Shinji

Yamasaki, Yasuhisa

Sakai, Takashi

Utaka, Masanori

et al. et al.

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Article abstract of DOI:10.1246/cl.1992.1417

Two platelet activating factors (PAF) were conveniently prepared from optically active epichlorohydrin via 5 steps in 15-16percent total yield.Four analogues containing oleoyl, propyl, p-trifluoromethylphenoxy, and N,N-dimethyldithiocarbamoyl groups were also prepared.

Full text of DOI:10.1246/cl.1992.1417

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