A Convenient Synthesis of Platelet-Activating Factors and Their Analogues from Chiral Epichlorohydrin

DOI: 10.1246/cl.1992.1417

Source and publish data:

Chemistry Letters p. 1417 - 1420 (1992)

Update date:2022-08-04

Topics:

Authors:

Tsuboi, Sadao

Takeda, Shinji

Yamasaki, Yasuhisa

Sakai, Takashi

Utaka, Masanori

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1992.1417

Two platelet activating factors (PAF) were conveniently prepared from optically active epichlorohydrin via 5 steps in 15-16percent total yield.Four analogues containing oleoyl, propyl, p-trifluoromethylphenoxy, and N,N-dimethyldithiocarbamoyl groups were also prepared.

Full text of DOI:10.1246/cl.1992.1417

Products guided by the article

Product name:Carbamodithioic acid, dimethyl-, 2-hydroxy-3-[(4-methoxyphenyl)methoxy]propyl ester, (S)-

Cas No:143996-96-7

R&D Labs maybe for 143996-96-7

Guangzhou Flower's Song Fine Chemical CO,. Ltd

Contact:+86-20-87475199

Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
Luzhou North Chemical Co., Ltd.

Contact:+86-830-2796784；+86-830-2796776

Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Hangzhou Dingyan Chem Co., Ltd

website:http://www.dingyanchem.com

Contact:86-571-87157530

Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
Zibo Jujin Chemical Industry Co., Ltd.（Dongming Jujin Chemical Industry Co., Ltd. ）

Contact:+86-533-2975022

Address:No.99 Shanquan Road, Zhangdian District

Relevant to this article

Stereoselective Alkylation of Cyclic and Acyclic Chiral β-Enamino Ketones Lithium Dianions: Synthesis of Either (R)- or (S)-Chiral 1,3-Diketones.

Doi:10.1016/S0957-4166(00)80373-0
(1993)
Iron-catalyzed chemoselective azidation of benzylic silyl ethers

Doi:10.1002/chem.201202984
(2012)
Doi:10.1002/hlca.19620450728
(1962)
Friedel-Crafts Cyclization of 2-(3-Indolylthio)propionic Acids. An Unusual Rearrangement Leading to 4-Sulfur-Substituted Tricyclic Indoles

Doi:10.1016/S0040-4039(00)61267-4
(1992)
Stereoselective Glucosidation of Podophyllum Lignans. A New Simple Synthesis of Etoposide

Doi:10.1021/jo00067a071
(1993)
Organoplatinum chemistry with a dicarboxamide-diphosphine ligand: Hydrogen bonding, cyclometalation, and a complex with two metal-metal donor-acceptor bonds

Doi:10.1021/om400780q
(2013)

Article Doi