VICARIOUS NUCLEOPHILIC SUBSTITUTION OF HYDROGEN IN PYRIDAZINES

DOI: 10.1016/S0040-4039(00)61286-8

Source and publish data:

Tetrahedron Letters p. 4787 - 4790 (1992)

Update date:2022-07-30

Topics:

Authors:

Ostrowicz, Andrzej

Baloniak, Sylwester

Makosza, Mieczyslaw

Rykowski, Andrzej

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Article abstract of DOI:10.1016/S0040-4039(00)61286-8

Pyridazines, 3-pyridazinones and 3,6-pyridazinediones readily undergo vicarious nucleophilic substitution of hydrogen (VNS) with carbanion of chloromethyl p-tolyl sulfone to form new carbon-carbon bonds.The reaction offers a novel approach to the synthesi

Full text of DOI:10.1016/S0040-4039(00)61286-8

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