Synthesis and Biological Activity of 3--5--1H-indole and Analogues: Agonists for the 5-HT1D Receptor

DOI: 10.1021/jm00045a006

Source and publish data:

Journal of Medicinal Chemistry p. 3023 - 3032 (1994)

Update date:2022-07-30

Topics:

Authors:

Castro, Jose L.

Baker, Raymond

Guiblin, Alexander R.

Hobbs, Sarah C.

Jenkins, Matthew

et al. et al.

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Article abstract of DOI:10.1021/jm00045a006

A novel series of 5-(1,1-dioxo-1,2,5-thiadiazolidin-2-yl)tryptamines was designed, synthesized, and evaluated as 5-HT_1D receptor agonists.Compounds such as 8d,f,k were identified which had comparable affinity, potency, and receptor selectivity

Full text of DOI:10.1021/jm00045a006

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Product name:1,2,5-Thiadiazolidine, 2-methyl-5-(4-nitrophenyl)-, 1,1-dioxide

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