
Tetrahedron p. 10645 - 10654 (1992)
Update date:2022-08-04
Topics:
Sha, Chin-Kang
Yang, Jeng-Fenn
Staudinger reaction of 9 with triphenylphosphine gave 2,4-dihydropyrrolo<3,4-b>indole 10.Treatment of 10 with di-tert-butyl dicarbonate and 4-dimethylaminopyridine gave 11.Diels-Alder reaction of 11 with 3,4-pyridyne gave cycloadducts 12 and 13, which were converted into ellipticine 1 and isoellipticine 2.New amino analogues of ellipticine 27 and 28 were also synthesized by this new route.Key words: Ellipticine, 2,4-Dihydropyrrolo<3,4-b>indole, Staudinger Reaction
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Doi:10.1039/c2ob26478a
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(2010)Doi:10.1016/S0040-4020(01)80322-7
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(2013)Doi:10.1016/S0040-4020(01)86265-7
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(1992)