REACTION OF METHYL DICHLOROACETATE WITH SUBSTITUTED BENZALDEHYDES UNDER THE CONDITIONS OF THE DARZENS CONDENSATION

Article abstract of DOI:10.1007/BF00863594

We have found that condensation of methyl dichloroacetate (1) with benzaldehyde, p-chloro- and p-bromobenzaldehyde in t-BuOH in the presence of t-BuOK yields methyl 3-aryl-3-chloro-2-oxopropionates (3-5).In the case of nitrobenzaldehydes the reaction prod