Nucleosides and nucleotides. 125. Synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro-2'-methylidene pyrimidine nucleosides

Article abstract of DOI:10.1080/15257779408013235

Reaction of 2'-deoxy-2'-methylidene-5'-O-trityluridine (1) with diethylaminosulfur trifluoride (DAST) in CH₂Cl₂ resulted in the formation of a mixture of (3'R)-2',3'-dideoxy-3'-fluoro-2'-methylidene derivative 3 and 2',3'-didehydro-2

Full text of DOI:10.1080/15257779408013235

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Nucleosides and Nucleotides. 125.
Synthesis and Biological Evaluation of
2′,3′-Dideoxy-3′-fluoro-2′-methylidene
Pyrimidine Nucleosides
Abdalla Elsayed A. Hassan a , Satoshi Shuto a & Akira Matsuda a
a Faculty of Pharmaceutical Sciences Hokkaido University , Kita-12,
Nishi-6, Kita-ku, Sapporo, 060, Japan
Published online: 23 Sep 2006.
To cite this article: Abdalla Elsayed A. Hassan , Satoshi Shuto & Akira Matsuda (1994) Nucleosides
and Nucleotides. 125. Synthesis and Biological Evaluation of 2′,3′-Dideoxy-3′-fluoro-2′-
methylidene Pyrimidine Nucleosides, Nucleosides and Nucleotides, 13:1-3, 197-211, DOI:
10.1080/15257779408013235
To link to this article: http://dx.doi.org/10.1080/15257779408013235
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