Nucleosides and nucleotides. 125. Synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro-2'-methylidene pyrimidine nucleosides

DOI: 10.1080/15257779408013235

Source and publish data:

Nucleosides and Nucleotides p. 197 - 211 (1994)

Update date:2022-08-02

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Authors:

Hassan Hassan

Shuto Shuto

Matsuda Matsuda

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Article abstract of DOI:10.1080/15257779408013235

Reaction of 2'-deoxy-2'-methylidene-5'-O-trityluridine (1) with diethylaminosulfur trifluoride (DAST) in CH₂Cl₂ resulted in the formation of a mixture of (3'R)-2',3'-dideoxy-3'-fluoro-2'-methylidene derivative 3 and 2',3'-didehydro-2

Full text of DOI:10.1080/15257779408013235

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