An Intramolecular 1,3-Dipolar Cycloaddition/Electrophilic Cyclization Sequence To Give Cyclic Ethers

DOI: 10.1021/jo00078a003

Source and publish data:

Journal of Organic Chemistry p. 7320 - 7321 (1993)

Update date:2022-08-04

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Authors:

Beebe, Xenia

Chippari, Cynthia L.

Kurth, Mark J.

Schore, Neil E.

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Article abstract of DOI:10.1021/jo00078a003

An intramolecular 1,3-dipolar cycloaddition/electrophilic cyclization sequence has been developed for the synthesis of cyclic ethers.This approach utilizes a diastereoselective nitrile oxide 1,3-dipolar cycloaddition to give furoisoxazoles, which undergo

Full text of DOI:10.1021/jo00078a003

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