Synthesis and Biological Activity of 4a,4"-Disubstituted Avermectins

DOI: 10.1021/jf00044a041

Source and publish data:

Journal of Agricultural and Food Chemistry p. 1786 - 1790 (1994)

Update date:2022-08-05

Topics: Synthesis Biological Activity Chemical Compounds Experimental

Authors:

Jones, Todd K.

Chu, Lin

Mrozik, Helmut

Slayton, Lyndia

Rafalko, Bryan

et al. et al.

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Article abstract of DOI:10.1021/jf00044a041

Allylic oxidation of avermectin B₁ and C4-substituted avermectin B₁ analogues at C_4a followed by derivatization of the C_4a oxygen provides compounds that have an improved safety profile, as judged bu mouse LD View More

Full text of DOI:10.1021/jf00044a041

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