A General Asymmetric Synthesis of (-)-α-Dimethylretrodendrin and Its Diastereomers

Article abstract of DOI:10.1021/jo00067a057

A Diels-Alder cycloaddition between the fumarate of methyl (R)-mandelate 14 and α-hydroxy-α'-aryl-o-quinodimethane 12 produced an exo cycloadduct 15 in 44percent yield which was converted to optically pure (-)-α-dimethylretrodendrin (21) and three of its