
Steroids p. 423 - 428 (1993)
Update date:2022-07-29
Topics: Thiols Conformational Analysis 1,4-Addition Reaction
Numazawa
Oshibe
Matsuzaki
Reactions of androst-4-ene-3,6,17-trione (1) and its 19-hydroxy or 19-oxo derivative (2 or 3), suicide substrates of aromatase, with thiols were initially studied. Treatment of 4-ene-3,6-diones 1-3 with benzyl-mercaptan in MeOH at room temperature gave th
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