Diastereomer differentiation during 1,2-addition of Grignard reagents under rotamer distribution control

DOI: 10.1016/S0957-4166(00)80410-3

Source and publish data:

Tetrahedron Asymmetry p. 1759 - 1762 (1993)

Update date:2022-08-03

Topics:

Authors:

Yoda Yoda

Kitayama

Takabe Takabe

Kakehi Kakehi

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Article abstract of DOI:10.1016/S0957-4166(00)80410-3

Construction of (R)-tertiary alcohols through diastereofacial differentiation under rotamer distribution control was accomplished with complete selectivity by means of simple nucleophilic addition of Grignard reagents to chiral α-ketoamides elaborated fro

Full text of DOI:10.1016/S0957-4166(00)80410-3

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