Journal of Medicinal Chemistry p. 3071 - 3077 (1995)
Update date:2022-08-05
Topics:
Schmidhammer, Helmut
Jennewein, Herwig K.
Krassnig, Roland
Traynor, John R.
Patel, Dinesh
et al.
A series of 3-hydroxy-substituted analogues (3-7) of the μ selective opioid antagonist cyprodime has been synthesized in order to evaluate the role of a hydroxy group at C-3 concerning μ opioid antagonist selectivity.Compounds 3-7 were tested in bioassays
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