Chemistry of Heterocyclic Compounds p. 945 - 948 (1993)
Update date:2022-08-05
Topics: Synthesis Compound Experimental Antiviral agent 9-Allyloxymethylguanine
Ozerov, A. A.
Brel', A. K.
A convenient method has been developed for the synthesis of 9-allyloxymethylguanine. The direct alkylation of the trimethylsilyl derivative of guanine allyloxymethyl chloride gives a 64 percent yield of 9- and 7-allyloxymethylguanine (3:1). A mixture of 9- and 7-allyloxymethyl-N-acetylguanine (7:4) can be obtained in 56 percent yield by the condensation of diacetylguanine with allyloxymethyl acetate in dimethyl sulfoxide in the presences of p-toluenesulfonic acid.
View MoreXinxiang Hongqi District Houyuan Trading Co., Ltd
Contact:86-373-3695376
Address:Xinxiang City, Henan Province, China
Nanjing distinctions Medical Technology Co., Ltd.
Contact:+86-15996203785 13914714059
Address:nanjing,jiangsu , China
ShangHai BMG Chemical Co., Ltd
Contact:+86-13524845543
Address:Room 602, no 291 sikai road shanghai
NanJing KaiHeng Chemical CO., LTD.
Contact:+86-25-85768391
Address:RM.1704, D, WANDA PLAZA, NO.110, MIDDLE JIANGDONG ROAD, NANJING, CHINA
Tianjin Jiuri New Materials Co., Ltd.
Contact:+86-22-58889220
Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Doi:10.1111/j.2042-7158.1994.tb03751.x
(1994)Doi:10.1016/j.tetlet.2013.12.110
(2014)Doi:10.1016/S0040-4039(00)61504-6
(1993)Doi:10.1002/anie.202109723
(2021)Doi:10.1016/j.carres.2009.07.008
(2009)Doi:10.1021/jo9003037
(2009)