Synthesis of 2',3'-Dideoxy-3'-C-(hydroxymethyl)-4'-thionucleosides as Potential Inhibitors of HIV

DOI: 10.1021/jo00086a032

Source and publish data:

Journal of Organic Chemistry p. 1783 - 1788 (1994)

Update date:2022-09-26

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Authors:

Branalt, Jonas

Kvarnstroem, Ingemar

Niklasson, Gunilla

Svensson, Stefan C. T.

Classon, Bjoern

Samuelsson, Bertil

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Article abstract of DOI:10.1021/jo00086a032

The synthesis of 2',3'-dideoxy-3'-C-(hydroxymethyl)-4'-thionucleosides is described.For the synthesis of the carbohydrate part, the configuration of the secondary hydroxyl group in (2S,3R)-1-O-(p-bromobenzyl)-3-(2'-propenyl)-1,2,4-butanetriol (1) was inve

Full text of DOI:10.1021/jo00086a032

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