Synthesis of biologically active N-acylated L-serine-containing D- glucosamine-4-phosphate derivatives of lipid A

DOI: 10.1248/cpb.41.1879

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1879 - 1881 (1993)

Update date:2022-07-29

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Authors:

Ikeda Ikeda

Asahara Asahara

Achiwa Achiwa

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Article abstract of DOI:10.1248/cpb.41.1879

New N-acylated L-serine-containing non-phosphorylated and phosphorylated D-glucosamine derivatives structurally corresponding to lipid A disaccharide backbone were synthesized. Compound 4,5 showed mitogenic activity.

Full text of DOI:10.1248/cpb.41.1879

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Product name:N-tetradecanoyl-O-<6-O-benzyloxymethyl-2-deoxy-4-O-diphenylphosphono-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-serine benzyl ester

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